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Canine Multifocal Retinopathy (CMR) is an eye disorder characterised by multiple areas of retinal degeneration, potentially causing a loss of central vision.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Canine Multifocal Retinopathy (CMR) is an eye disorder characterised by multiple areas of retinal degeneration, potentially causing a loss of central vision. This variant of the disorder, CMR3, occurs specifically in the Lapponian Herder, Swedish Lapphund and the Finnish Lapphund, and is caused by a recessive mutation to the gene BEST1.
Clinical features
On veterinary examination, clinical signs of CMR include multiple tan-pink subretinal patches ("blisters") in both the tapetal and the non-tapetal fundus along with focal areas of tapetal hyper-reflectivity. The disorder does not typically lead to blindness.
Additional information
References
Pubmed ID: 21197113
Omia ID: 1554