57,48 47,50 excl. VAT

H748

Mucopolysaccharidosis VII (MPS VII) is a hereditary lysosomal storage disease and belongs to a group of genetic disorders of glycosaminoglycan catabolism resulting in lysosomal storage.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Mucopolysaccharidosis VII (MPS VII) is a hereditary lysosomal storage disease and belongs to a group of genetic disorders of glycosaminoglycan catabolism resulting in lysosomal storage. Affected dogs have insufficient activity of the enzyme heparan N-sulfatase which contributes to breaking down heparan sulfate.

Clinical features

Affected dogs have symptoms such as ataxia, head tremors, swaying and abnormal eye movement. The clinical signs develop around the age of 3 years.

Additional information

References

Pubmed ID: 9521879

Omia ID: 667

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

Related products