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The enzyme CYP1A2 is involved in metabolism; the body’s system for processing chemical compounds.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
The enzyme CYP1A2 is involved in metabolism; the body’s system for processing chemical compounds. Research has shown that certain Beagles are affected by a recessive mutation to the CYP1A2 gene, leaving them less able to process certain specific drugs such as the memory-enhancing compound AC-3933.
Clinical features
Affected dogs have a decreased functionality of the CYP1A2 enzyme, processing certain drugs differently, but are expected to appear mostly normal and healthy.
Additional information
References
Pubmed ID: 15564884
Omia ID: 1405