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Macular Corneal dystrophy (MCD) is an eye condition in Labrador Retrievers that causes the corneas to gradually become cloudy, leading to worsening vision.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Macular Corneal dystrophy (MCD) is an eye condition in Labrador Retrievers that causes the corneas to gradually become cloudy, leading to worsening vision. It is most likely caused by a recessive mutation in a comparative candidate gene (CHST6).
Clinical features
Onset of MCD is generally between 4.5 and 6 years of age. The cornea becomes gradually cloudy, and develops multiple off-white to yellow-brown opaque spots of varying sizes.
Additional information
References
Pubmed ID: 26585178
Omia ID: 2071