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Lavender Foal Syndrome (LFS, also called Lethal Coat Colour Dilution) is a severe, recessively-inherited neurological disorder in Arabian horses.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Lavender Foal Syndrome (LFS, also called Lethal Coat Colour Dilution) is a severe, recessively-inherited neurological disorder in Arabian horses. Affected foals are often stillborn, and suffer greatly if even if they survive, being unable to stand or nurse properly. Surviving lavender foals are therefore usually euthanized. The condition is named for the light, “diluted” coat colour that affected foals have. LFS is caused by a mutation to the gene MYO5A.
Clinical features
LFS typically results in stillbirth. Surviving foals cannot stand, and in some cases are unable to roll to lie upright. Other features include a backwards-arched neck, stiffly extended legs, seizures, and a distinctive lightened coat, which can be described as pale gray, pewter, light chestnut or lavender.
Additional information
References
Pubmed ID: 20419149
Omia ID: 1501
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