€57,48 €47,50 excl. VAT
Laryngeal Paralysis with Polyneuropathy (LPPN) is a neural disorder which causes an altered voice, difficulty swallowing and loss of coordination.
10 working days
From €5,95 shipping and administration per order (incl. VAT)
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Laryngeal Paralysis with Polyneuropathy (LPPN) is a neural disorder which causes an altered voice, difficulty swallowing and loss of coordination. This variant has been observed in the Labrador Retriever, Leonberger and Saint Bernard, and is caused by a recessive mutation to the gene CNTNAP1.
Clinical features
The main symptom of LPPN is difficult, noisy or raspy breathing. Other signs can include altered barking, difficulty swallowing, uncoordinated walking, stumbling or tripping and atrophy of the limb muscles.
Additional information
References
Pubmed ID: 33261176
Omia ID: 2301