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H991

Dilated Cardiomyopathy (DCM) is a heart disorder characterised by enlargement of the heart (especially of the left ventricle), poor myocardial contractility, and congestive heart failure.

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Specifications

Breeds

, ,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Dilated Cardiomyopathy (DCM) is a heart disorder characterised by enlargement of the heart (especially of the left ventricle), poor myocardial contractility, and congestive heart failure. This variant of the disorder, known as Juvenile Dilated Cardiomyopathy (JDCM), occurs in young dogs of the Manchester Terrier and English Toy Terrier breeds. It is caused by a recessive disorder to the gene ABCC9. The disorder is severe, and can cause sudden death of juvenile affected dogs.

Clinical features

Signs of congestive heart failure caused by DCM in affected dogs can include rapid or strained breathing while resting, restlessness, general weakness, decreased appetite and vomiting, pale gums and sudden death. Veterinary examination can provide a proper diagnosis. JDCM occurs in juvenile dogs, often before the age of 2 years.

Additional information

References

Pubmed ID: 37239348

Omia ID: 2710

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2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

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