€57,48 €47,50 excl. VAT
Inflammatory Myopathy in the Dutch Shepherd is a severe, progressive neuromuscular disease that results in weakness, muscle atrophy and an inability to walk.
10 working days
€5,95 shipping and administration per order (incl. VAT)
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Inflammatory Myopathy in the Dutch Shepherd is a severe, progressive neuromuscular disease that results in weakness, muscle atrophy and an inability to walk. The disorder is caused by a recessive mutation to the gene SLC25A12. A related variant, known as Cerebellar Degeneration-Myositis Complex, is found in the Nova Scotia Duck Tolling Retriever.
Clinical features
Affected dogs present between the ages of 3 and 9 months with progressively developing muscle weakness and atrophy. Signs may include stiffness of the limbs, tremors and an increasing inability to walk. Due to the severe and progressive nature of the disease, euthanasia on humane grounds is likely to be necessary by the age of 2 years.
Additional information
References
Pubmed ID: 31594244
Omia ID: 2294
Related products
-
- Great Dane
- SLC27A4
- Integumentary system
-
- Dachshund, Parson Russell Terrier, Smooth Fox Terrier, Jack Russell Terrier
- KCNJ10
- Nervous system
-
- All Breeds
- None
-
- English Cocker Spaniel, English Springer Spaniel, French Spaniel, German Shorthaired Pointer, English Pointer
- GDNF
- Nervous system
