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Ichthyosis is a disease of the skin, causing itch, hair loss and the formation of dry, flaky “scales”.
10 working days
Swab, Blood EDTA, Blood Heparin, Semen, Tissue
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Ichthyosis is a disease of the skin, causing itch, hair loss and the formation of dry, flaky “scales”. It also leaves the skin vulnerable to fungal infection. This variant of the disorder, known as Autosomal Recessive Congenital Ichthyosis (ARCI) is found in the American Bulldog, and is caused by a recessive mutation to the gene NIPAL4.
Affected puppies present within the first few weeks after birth with dishevelled coats, white or brown scaling and reddened skin with brown discolorations. The condition may worsen slightly as the dog grows to adulthood, and may be complicated by fungal infection by e.g. Malassezia yeast. Malassezia infection can in turn cause an unpleasant odour.
This test only detects one mutation therefore a dog can still develop ichthyosis from other mutations.
Pubmed ID: 28122049
Omia ID: 1980