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H365

Myelin is a fat-rich compound that surrounds the axon of certain nerve cells and thus enables faster propagation of action potentials via a saltatory conduction.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

Myelin is a fat-rich compound that surrounds the axon of certain nerve cells and thus enables faster propagation of action potentials via a saltatory conduction. Insufficient myelin disrupts this process.

Clinical features

Clinical signs were first observed between 12 and 14 days of age. The affected pups were able to ambulate, but showed a "hopping" gait in the hind limbs.

Additional information

References

Pubmed ID: 24272703

Omia ID: 526

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