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Hypocatalasia (known variously as Acatalasia, Catalasia Deficiency, Hypocatalasemia, Acatalasemia, Takahara’s Disease or CAT) is a disorder in which the body does not produce enough of the enzyme catalase, which can result in ulcers of the mouth.

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Specifications

Breeds

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Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

Hypocatalasia (known variously as Acatalasia, Catalasia Deficiency, Hypocatalasemia, Acatalasemia, Takahara’s Disease or CAT) is a disorder in which the body does not produce enough of the enzyme catalase, which can result in ulcers of the mouth. A semi-dominant mutation causing the disease has been observed in a range of breeds, including the Beagle, American Foxhound and Miniature Poodle.

Clinical features

Affected dogs are at increased risk of oral ulcers and resulting complications, including gangrene of the mouth and tooth loss.

Additional information

References

Pubmed ID: 11137458

Omia ID: 1138

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3. Results

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