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Hyperkalemic periodic paralysis (Hypp) is caused by a mutation in the muscle’s sodium channel gene.
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Hyperkalemic periodic paralysis (Hypp) is caused by a mutation in the muscle’s sodium channel gene. As a result the muscles contract involuntarily with blood potassium changes. This can occur with stress or fasting followed by eating high potassium feed like alfalfa.
Horses affected by HYPP have severe muscle problems following exercise. They show episodes of muscle twitching and shaking. The signs usually begin by two to three years of age. Severely affected horses may have a hard time swallowing or make loud breathing noises. Sometimes sudden death can occur following a severe episode.
Even horses which are heterozygous may show symptoms of the disease. HYPP horses may appear normal between episodes.
Pubmed ID: 1338908
Omia ID: 785