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Hereditary Equine Regional Dermal Asthenia (HERDA), also known as Hyperelastosis Cutis (HC) is a tissue disorder in the American Quarter Horse that causes loose, fragile skin.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Hereditary Equine Regional Dermal Asthenia (HERDA), also known as Hyperelastosis Cutis (HC) is a tissue disorder in the American Quarter Horse that causes loose, fragile skin. The disorder is caused by a recessive mutation to the gene PPIB.
While the disorder occurs primarily in the American Quarter Horse, it has also been observed in Arabian and American Paint horses with Quarter Horse ancestry.
Clinical features
The primary symptom of HERDA is loose skin that can be described as stretchy or elastic. The skin is more fragile than normal, sloughing easily and causing ulcers, hematomas and scarring. The symptoms usually become apparent between 1 and 2 years of age, when the horse starts its saddle training. Owners typically elect for euthanasia on humane grounds.
Additional information
References
Pubmed ID: 17498917
Omia ID: 327