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Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding. It is caused by an X-linked recessive mutation to the gene F9. There are many known variants of Haemophilia B, each specific to a particular dog breed. The variant analysed in this test is found in the Lhasa Apso.
Clinical features
Affected dogs are prone to uncontrolled bleeding after injury or surgery, and may develop spontaneous bleeding. Blood analysis will confirm a lack of Factor IX activity and delayed clotting times.
Additional information
References
Pubmed ID: 8896410
Omia ID: 438