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Haemophilia B, also called Factor IX Deficiency, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding.
10 working days
Specifications
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
General information
Haemophilia B, also called Factor IX Deficiency, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding. It is caused by an X-linked recessive mutation to the gene F9. There are many known variants of Haemophilia B, each specific to a particular dog breed. The variant analysed in this test is found in the Rhodesian Ridgeback.
Clinical features
Affected dogs are prone to uncontrolled bleeding after injury or surgery, and may develop spontaneous bleeding. Blood analysis will confirm a lack of Factor IX activity.
Additional information
References
Pubmed ID: 20303304
Omia ID: 438