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Goniodysgenesis and glaucoma is a complex eye disease caused by multiple genetic factors.
19 working days
Swab, Blood EDTA, Blood Heparin, Semen, Tissue
|Mode of Inheritance|
|Also known as||
Pectinate ligament abnormality (PLA), Primary closed-angle glaucoma (PCAG)
Goniodysgenesis and glaucoma is a complex eye disease caused by multiple genetic factors. The association has been established with a mutation in the OLFML3 gene.
Also known as pectinate ligament abnormality (PLA) and primary closed‐angle glaucoma (PCAG).
The abnormality of the anterior chamber of the eye has been associated with glaucoma and blindness. This causes a.o. severe pain, light sensitivity, eyelid winking spasms and consequential behavioral changes.
The association of this variant with goniodysgenesis in Border Collies is strong, but it is not complete. Research has shown that the chance of this marker identifying Border Collies that are actually going to be affected is approximately 69%.
Omia ID: 1223