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Primary Open Angle Glaucoma (POAG) is an autosomal recessive disorder that causes blindness.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Primary Open Angle Glaucoma (POAG) is an autosomal recessive disorder that causes blindness. This is due to a mutation in the ADAMTS10 protein that can lead to increased pressure in the eye, leading to nerve damage, lens subluxation and vision loss. This variant is found in the Beagle.
Clinical features
POAG is usually diagnosed, when the dog start to experience more significant vision impairment. Earlier signs can include the formation of cataracts, impaired vision and increased pressure inside the eye, which can be measured at the veterinary clinic.
Additional information
POAG in the Norwegian Elkhound is usually diagnosed in middle-aged to elderly dogs, when they start to experience more significant vision impairment. Earlier signs can include the formation of cataracts, impaired vision and increased pressure inside the eye, which can be measured at the veterinary clinic.
References
Pubmed ID: 21379321
Omia ID: 1870