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Nephropathy is the collective name for kidney diseases.

10 working days







Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance


Also known as

Year Published

General information

Nephropathy is the collective name for kidney diseases. This test analyzes a variant of nephropathy, Autosomal Recessive Hereditary Nephropathy (ARHN) that occurs in the English Cocker Spaniel. The disorder is caused by a recessive mutation to the gene COL4A4. A similar variant also occurs in the English Springer Spaniel.

Clinical features

ARHN causes kidney failure in affected dogs. Symptoms of kidney failure can include weight loss, increased micturition, increased thirst, lethargy, loss of appetite, vomiting, bad breath and dehydration. Blood analysis can amongst others show increased levels of creatinine and SDMA. The onset is rapid, and symptoms may be severe enough to require euthanasia.

Additional information

Hereditary nephropathy can also be caused by other mutations.


Pubmed ID: 17552442

Omia ID: 710

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2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

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