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H980

Exfoliative Cutaneous Lupus Erythematosus (ECLE) is a severe immune disorder affecting the skin, causing skin lesions, crusts and hair loss.

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Specifications

Breeds

,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Exfoliative Cutaneous Lupus Erythematosus (ECLE) is a severe immune disorder affecting the skin, causing skin lesions, crusts and hair loss. The disease is caused by a recessive mutation to the gene UNC93B1, and is found in the German Shorthaired Pointer, Vizsla and related hunting dogs.

Clinical features

Affected dogs present between the ages of 6 months and 3 years with the formation of skin scales, mainly on the face, ears and back. The skin may develop patchy, reddened lesions and clinging crusts, as well as general hair loss on affected areas. In later stages, some affected dogs may also experience severe joint pain.

Additional information

References

Pubmed ID: 32028618

Omia ID: 1609

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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