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H385

Anhidrotic Ectodermal Dysplasia (XHED) is a skin and tissue disorder that results in lack of hair and underdeveloped teeth, and can leave affected dogs vulnerable to parasites and infections.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Anhidrotic Ectodermal Dysplasia (XHED) is a skin and tissue disorder that results in lack of hair and underdeveloped teeth, and can leave affected dogs vulnerable to parasites and infections. It is caused by an X-linked recessive mutation to the gene EDA. The variant of the disease in this test is found in the German Shepherd. Other variants have been observed in the Dachshund and certain mixed breeds.

Clinical features

Affected dogs have no sweat glands or secondary hairs, and lack hair on the forehead and on the lower back. They also lack many teeth, with remaining teeth being unusually cone-shaped. Other complications from the condition can include chronic discharge from the eyes and nose, as well as susceptibility to airway infections and skin parasites.

Additional information

References

Pubmed ID: 16151697

Omia ID: 543

How does it work?

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2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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