X-linked ectodermal dysplasia is characterised by abnormal hair, teeth, nails or sweat gland function. These tissue types all share a similar tissue origin: the ectoderm. Multiple mutations in the DNA can cause this disease and in case the mutation(s) are on the X-chromosome, it is X-linked.
Abnormal growth of tissue and organs derived from ectoderm: hair, teeth, nails, sweat glands, ears, eyes, lips, mucous membranes of the mouth or nose, and the central nervous system.
Male offspring are at high risk due to the single X-chromosome present.