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Bilateral Deafness with Vestibular Dysfunction is a neurological disorder occurring in the Doberman Pinscher, which causes loss of hearing and difficulties with balancing and walking.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Bilateral Deafness with Vestibular Dysfunction is a neurological disorder occurring in the Doberman Pinscher, which causes loss of hearing and difficulties with balancing and walking. In the Doberman breeding community, the disorder is colloquially known as DINGS2. It is caused by a recessive mutation to the gene MYO7A.
Clinical features
Affected puppies typically develop symptoms within the first few weeks of life. Signs include difficulty nursing, wobbling or tilting of the head, loud and inconsolable crying out of apparent discomfort/distress, signs of vestibular dysfunction such as an absent startle reflex, and an inability to stand or walk properly.
Additional information
References
Pubmed ID: 31097876
Omia ID: 2148