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In cats, the growth and structure of coat hairs is partially governed by the gene for lysophosphatidic acid receptor 6 (LPAR6).
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Specifications
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Year Published |
General information
In cats, the growth and structure of coat hairs is partially governed by the gene for lysophosphatidic acid receptor 6 (LPAR6). A recessive mutation to this gene is responsible for the distinctive curly coat of the Cornish Rex breed.
Clinical features
Affected cats develop fur without guard hairs and awn hairs, which normally form the outer layers of a coat. Instead, their coat is exclusively made up of down hairs, which are extremely fine and naturally wavy or curly, typically falling in washboard-like waves. As these hairs are relatively thin and fragile, affected cats are somewhat prone to developing bald patches, and are more sensitive to cold temperatures than other cats.
Additional information
References
Pubmed ID: 23826204
Omia ID: 1684