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Craniomandibular Osteopathy (CMO), also known as Lion Jaw, is a developmental bone disorder that causes bony lesions on the skull.
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Specifications
| Breeds | Cairn Terrier, Scottish Terrier, West Highland White Terrier |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Craniomandibular Osteopathy (CMO), also known as Lion Jaw, is a developmental bone disorder that causes bony lesions on the skull. Occurring in West Highland White Terriers, Scottish Terriers and Cairn Terriers, it is caused by an incompletely dominant mutation to the gene SLC37A2.
Because of its occurance in the West Highland White Terrier, the disorder is also known as Westie Jaw.
A closely related variant of the disorder is found in the Basset Hound.
Clinical features
CMO begins manifesting in affected dogs between 4 and 8 months of age. Signs include swelling of the jaw, difficulty opening the jaw, pain, a lack of apetite and periodic fever. Bony lesions develop on the skull, mainly on the jawbone. Symptoms usually recede when the dog has finished its growth period.
Additional information
References
Pubmed ID: 27187611
Omia ID: 2244