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Congenital myasthenic syndrome (CMS) is an inherited neuromuscular disorder characterised by severe generalized skeletal muscle weakness and fatigue, usually it manifests itself with exertion.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Congenital myasthenic syndrome (CMS) is an inherited neuromuscular disorder characterised by severe generalized skeletal muscle weakness and fatigue, usually it manifests itself with exertion.
Clinical features
Affected dogs are able to run normally for 5–30 min after which they take shorter and shorter strides and eventually fall down with flexed fore- and hindlegs. After some minutes rest, they are able to walk and run again for variable periods of time before the signs reappear.
Additional information
References
Pubmed ID: 17586598
Omia ID: 2072