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K303

Dominant White and White Spotting are controlled by the KIT-gene.

20 working days

€5,95 shipping and administration per order (incl. VAT)

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Dominant White and White Spotting are controlled by the KIT-gene. Dominant white is also described as the W-locus and White Spotting as the S-locus. The KIT-gene has three variants (alleles). The DW allele is dominant over the alleles Ws and N; allele Ws is dominant over allele N.

Clinical features

The dominant allele DW results in a white coat colour. One or two copies of the DW allele will result in a white-coated cat with varying degrees of hearing impairment. The allele Ws in white spotting and the allele N has no effect on the coat colour.

Additional information

The gene/genes controlling the pattern of White Spotting is still unknown. Additionally, not all white spots or patterns result from the KIT-gene as other genes can also have mutations that result in depigmentation phenotypes. Dominant White is distinct from albinism (C-locus) which results from a mutation in the TYR gene that has no known impact on hearing.

References

Pubmed ID: 25085922

Omia ID: 209

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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