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The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations.
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Specifications
| Breeds | American Quarter Horse, Lipizzaner, Appaloosa, Haflinger, Noriker |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the Dominant White phenotype may be referred to as Splashed White, White Spotting, Tobiano or Sabino, among others.
The specific variant analysed in this test, known as Sabino 1 (SB1), is caused by a semi-dominant mutation to the gene KIT. It has been observed in the American Quarter Horse, Appaloosa, Haflinger, Lipizzaner and Noriker
Clinical features
The sabino pattern is described as irregular spotting usually on the legs, belly and face, often with roaning around the edges of the white markings. The allele SB1 is semi-dominant; one copy of SB1 allele results in horses with broken Sabino markings and possibly only a small amount of white. Two copies of the SB1 allele result in at least 90% white, also referred to as Sabino-white.
Additional information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
Dominant White can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
References
Pubmed ID: 16284805
Omia ID: 209
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