57,48 47,50 excl. VAT

Only available in bundles

H632

Coat colour in dogs is controlled by a wide range of different genes working together.

10 working days

€5,95 shipping and administration per order (incl. VAT)

Only available in bundles

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Extension, or E-Locus, corresponds to the gene ‘melanocortin 1 receptor’ (MC1R), which is involved in the regulation of pigment production. Mutations affecting the E-locus often result in a lightening of the coat, from black or brown to red, yellow or even white.

This E-locus variant, designated as e^2, is a recessive mutation observed in the Australian Cattle Dog. Related variants are known to occur in the Irish Setter, Labrador Retriever, Golden Retriever, and in the Husky.

Clinical features

Affected Australian Cattle Dogs (e/e) have a cream coat colour instead of the breed-typical blue or red.

Additional information

Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a dog's coat colour genetics.

References

Pubmed ID: 29932470

Omia ID: 1199

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

Related products