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The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations.
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Specifications
Breeds | |
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Gene | |
Organ | |
specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
General information
The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the Dominant White phenotype may be referred to as Splashed White, White Spotting, Tobiano or Sabino, among others.
The specific variant analysed in this test, known as Dominant White 10 (W10), is caused by a dominant mutation to the gene KIT. It has been observed in the American Quarter Horse.
Clinical features
Dominant White 10 is extremely variable in expression. Colouration can range anywhere between white legs and facial markings to an almost entirely white body.
Additional information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
Dominant White can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
References
Pubmed ID: 19456317
Omia ID: 209