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The cream dilution gene (SLC45A2, previously known as MATP) has an effect on both red and black pigment and dilutes the basic coat colour to lighter coat shades.

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Specifications

Breeds

Gene

Organ

specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

The cream dilution gene (SLC45A2, previously known as MATP) has an effect on both red and black pigment and dilutes the basic coat colour to lighter coat shades. In several breeds this is considered a desirable trait. The cream mutation shows incomplete dominance, meaning that one copy of the Cr allele produces a dilute colour and two copies of the Cr allele produces a more extreme dilute colour.

Clinical features

A single dose dilution (one copy of Cr allele) results in palomino, buckskin or smoky black. The effect on black pigment might be very subtle. A double dose dilution (two copies of Cr allele) results in cremello, perlino or smoky cream. They are also called “double-dilutes” or “blue-eyed cream” and they share a number of characteristics. Their eyes are pale blue, paler than the unpigmented blue eyes associated with white colour or white markings, and the skin is rosy-pink.

Additional information

References

Pubmed ID: 12605854

Omia ID: 1344

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