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Coat colour in cats is controlled by a wide range of different genes working together.
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Specifications
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
General information
Coat colour in cats is controlled by a wide range of different genes working together. A brown or ruddy coat colour (typically known as ‘Chocolate’ or ‘Cinnamon’) is caused by a recessive mutation to the gene TYRP1. There are two variant mutations: b, associated with Chocolate, and b^l, associated with Cinnamon. The b mutation is itself dominant over b^l.
Clinical features
Affected cats that would otherwise have a black or dark coat are expected to develop a lighter brown coat instead. A genotype of b/b or b/b^l results in a chocolate or chestnut coat colour. A genotype of b^l/b^l results in a lighter colour known as cinnamon or simply red.
Additional information
Coat colour is an complex trait that relies on the interaction of many different genes. Several different tests may be required to form the most accurate image of an animal's coat colour genetics.
References
Pubmed ID: 16104383
Omia ID: 1249