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Coat colour in cats is controlled by a wide range of different genes working together.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Coat colour in cats is controlled by a wide range of different genes working together. These genes are often referred to as “loci”. The C-Locus, a.k.a. Colour Locus, corresponds to the gene for tyrosinase (TYR). Recessive mutations to TYR can cause various degrees of Type 1 Oculocutaneous Albinism (OCA1), a failure to produce pigment, which leads to a silvery-white coat and light-coloured eyes. This can range between the distinctive point colouration of the Siamese cat, to full albinism.
The mutation analysed in this test, designated as “c”, is one of two that results in a fully albino coat. Together with the “c2” mutation, it is recessive to all other C-Locus alleles.
Clinical features
Affected cats are fully albino, with a white coat, blue eyes and a reddish pupil due to a lack of tapetum.
Additional information
Coat colour is an complex trait that relies on the interaction of many different genes. Several different tests may be required to form the most accurate image of a cat's coat colour genetics
References
Pubmed ID: 16573534
Omia ID: 202