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H356

The skeletal dysplasias are disorders of the bone and cartilage tissues.

10 working days

Specifications

Breeds

,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

The skeletal dysplasias are disorders of the bone and cartilage tissues. Chondrodysplasia, disproportionate short-limbed is caused by decreased chondrocyte proliferation in width and contains areas of abnormal cell column formation alternated with wide areas of matrix.

Clinical features

Dogs affected with chondrodysplasia suffer from disproportionate short stature dwarfism of varying severity.  Radiographic changes included flaring and increased width of the distal metaphyses of the radius and ulna, delayed ossification of the cuboid bones of the carpus, and reduction in length of the vertebral bodies.

Additional information

References

Pubmed ID: 24086591

Omia ID: 1886

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