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The skeletal dysplasias are disorders of the bone and cartilage tissues.
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Specifications
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Year Published |
General information
The skeletal dysplasias are disorders of the bone and cartilage tissues. Chondrodysplasia, disproportionate short-limbed is caused by decreased chondrocyte proliferation in width and contains areas of abnormal cell column formation alternated with wide areas of matrix.
Clinical features
Dogs affected with chondrodysplasia suffer from disproportionate short stature dwarfism of varying severity. Radiographic changes included flaring and increased width of the distal metaphyses of the radius and ulna, delayed ossification of the cuboid bones of the carpus, and reduction in length of the vertebral bodies.
Additional information
References
Pubmed ID: 24086591
Omia ID: 1886