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Bandera’s neonatal ataxia (BNAt) is an autosomal recessive disease of Coton de Tulear dogs.

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Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Bandera’s neonatal ataxia (BNAt) is an autosomal recessive disease of Coton de Tulear dogs. Ataxia is characterised by uncoördinated movements. The genetic mutation on the GRM1 gene plays a role in the neurologic disorder.

Clinical features

Neurologic research indicated head titubation, intention tremors, severe gait and ocular ataxia at two weeks of age. Most puppies are unable to walk and use propulsive movements for goal-oriented activities. The puppies would fall to lateral recumbency with consecutive decerebellate paddling and posturing.

Additional information

References

Pubmed ID: 21281350

Omia ID: 78

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