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Bandera’s neonatal ataxia (BNAt) is an autosomal recessive disease of Coton de Tulear dogs.
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Specifications
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Gene | |
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specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
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General information
Bandera’s neonatal ataxia (BNAt) is an autosomal recessive disease of Coton de Tulear dogs. Ataxia is characterised by uncoördinated movements. The genetic mutation on the GRM1 gene plays a role in the neurologic disorder.
Clinical features
Neurologic research indicated head titubation, intention tremors, severe gait and ocular ataxia at two weeks of age. Most puppies are unable to walk and use propulsive movements for goal-oriented activities. The puppies would fall to lateral recumbency with consecutive decerebellate paddling and posturing.
Additional information
References
Pubmed ID: 21281350
Omia ID: 78