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Canine Complement 3 (C3) deficiency is a metabolic disorder in the Brittany Spaniel that leaves affected dogs vulnerable to infections.
10 working days
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Canine Complement 3 (C3) deficiency is a metabolic disorder in the Brittany Spaniel that leaves affected dogs vulnerable to infections. It is caused by a recessive mutation to the C3 gene.
Clinical features
Particularly when young, affected dogs are likely to experience recurrent bacterial infections such as pneumonia, urinary tract infections and uterine tract infections. They are also more prone to Membranoproliferative Glomerulonephritis (MPGN), which can cause kidney damage and failure.
Additional information
References
Pubmed ID: 9510185
Omia ID: 155
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