Knowledge Base

PSSM1 (Polysaccharide Storage Myopathy)

PSSM1 - Polysaccharide Storage Myopathy Polysaccharide Storage Myopathy (PSSM) is a group of muscle disorders found in various horse breeds, particularly in Quarter Horses, Draft breeds, and Warmbloods. This condition leads to abnormal storage of glycogen (sugar) in the muscles, causing muscle pain, stiffness, and, in severe cases, muscle atrophy....

Dwarfism ACAN D1, D2, D3*, D4 and D5

Dwarfism ACAN D1, D2, D3*, D4 and D5 Miniature horses with chondrodysplastic dwarfism (ACAN dwarfism) are significantly shorter than expected for their age. The ACAN gene encodes a proteoglycan essential for normal cartilage and bone development, and mutations in this gene cause varying degrees of skeletal dysplasia in horses. Horses...

Disorders of Sexual Development (DSD) and Repeated Early Embryonic Loss (REEL)

Disorders of Sexual Development (DSD) and Repeated Early Embryonic Loss (REEL) There are a lot of reasons for a horse to be less fertile or infertile. Two groups of causes are the Disorders of Sexual Development (DSD) and the cases where a horse is fertile but it repeatedly loses the...