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Feline Autoimmune Lymphoproliferative Syndrome (FALPS or ALPS) is a severe immune disorder in young cats that results in swollen lymph nodes and abdomen, anemia, weight loss and ultimately death.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Feline Autoimmune Lymphoproliferative Syndrome (FALPS or ALPS) is a severe immune disorder in young cats that results in swollen lymph nodes and abdomen, anemia, weight loss and ultimately death. The disease is caused by a recessive mutation to the gene FASLG, and is found in the British Shorthair and related breeds.
Clinical features
Kittens with ALPS start showing symptoms at around 6-8 weeks of age. Affected kittens develop enlarged lymphnodes, enlarged spleen, no red blood cells. Furthermore the kittens show abdominal distension, lethargy and weight loss.
Additional information
References
Pubmed ID: 27770190
Omia ID: 2064
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