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Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare lymphoproliferative disease and has only been identified in British Shorthair cats so far.

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Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare lymphoproliferative disease and has only been identified in British Shorthair cats so far. In ALPS, the growth of lymphocytes is disrupted which results in an accumulation of lymphocytes in the lymphatic system leading to severe health difficulties.

Clinical features

Kittens with ALPS start showing symptoms at around 6-8 weeks of age. Affected kittens develop enlarged lymphnodes, enlarged spleen, no red blood cells. Furthermore the kittens show abdominal distension, lethargy and weight loss.

Additional information

References

Pubmed ID: 27770190

Omia ID: 2064

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