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Hair Shaft Dysplasia is a disorder that affects the structure of hair, causing broken/split hairs, hair loss and potentially skin discomfort.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Hair Shaft Dysplasia is a disorder that affects the structure of hair, causing broken/split hairs, hair loss and potentially skin discomfort. In domestic cats, two different recessive mutations to the gene DSG4 can cause hair shaft dysplasia. This test analyses the first variant, also designated as c.76del.
Clinical features
Affected cats experience general hair loss within the first months of life, particularly along the ears, face, back and legs. Their hairs are short and often split or broken, with bulbous swellings on the shafts on microscopic examination. Likewise, affected cats’ whiskers may be short and broken.
Additional information
References
Pubmed ID: 34878611
Omia ID: 2452