€57,48 €47,50 excl. VAT
Coat colour in cats is controlled by a wide range of different genes working together.
10 working days
€5,95 shipping and administration per order (incl. VAT)
Specifications
Breeds | |
---|---|
Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
General information
Coat colour in cats is controlled by a wide range of different genes working together. These genes are often referred to as “loci”. The C-Locus, a.k.a. Colour Locus, corresponds to the gene for tyrosinase (TYR). Recessive mutations to TYR can cause various degrees of Type 1 Oculocutaneous Albinism (OCA1), a failure to produce pigment, which leads to a silvery-white coat and light-coloured eyes. This can range between the distinctive point colouration of the Siamese cat, to full albinism.
The mutation analysed in this test, designated as “cb”, is responsible for Burmese-type sepia colouration. It is recessive to the normal genotype (“C”), but dominant over the “c” and “c2” albino mutations. A cat that carries one cs and one cb allele will display a mink coat instead.
Clinical features
Clinical features are darkened extremities of the body. The pattern is similar to Siamese-type point colouration, but with a lower contrast, a darker coat and yellow or green instead of blue eyes.
In Bengal cats, this mutation results in a Snow coat.
Additional information
Coat colour is an complex trait that relies on the interaction of many different genes. Several different tests may be required to form the most accurate image of a cat's coat colour genetics.
References
Pubmed ID: 15771720
Omia ID: 202