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Ichthyosis in dogs is a condition of the skin.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Ichthyosis in dogs is a condition of the skin. It causes extremely dry, thickened skin with flakes/scales. It is typically caused by a genetic mutation that causes defective or altered expression of the protein filaggrin. This variant, documented in a German Shepherd, is a result of a defect in the gene ASPRV1.
Clinical features
Onset of the condition is shortly after birth. Affected dogs develop patches of thin fur and greyish flakes or scales on the skin. The skin underneath is red, irritated and itchy.
Additional information
References
Pubmed ID: 28249031
Omia ID: 2099