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Polyneuropathy is a neural disorder that affects the peripheral nervous system (the nerves outside the spinal cord and brain).
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Polyneuropathy is a neural disorder that affects the peripheral nervous system (the nerves outside the spinal cord and brain). This variant of the disease, LPN2, occurs in the Leonberger. It is caused by an incompletely dominant mutation to the gene GJA9.
Clinical features
Affected dogs present with weakness, muscle atrophy, difficulty breathing and a change in barking pitch.
Additional information
References
Pubmed ID: 28841859
Omia ID: 2119