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As in humans, Narcolepsy in dogs is a long-term sleep disorder resulting in lethargy and sudden bouts of sleep.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
As in humans, Narcolepsy in dogs is a long-term sleep disorder resulting in lethargy and sudden bouts of sleep. Canine narcolepsy is a recessive disorder caused by a mutation to the HCRTR2 gene. The variant analysed in this test is found in the Doberman. Related variants occur in the Dachshund and the Labrador Retriever.
Clinical features
Narcolepsy is neither progressive nor life-threatening. Narcolepsy affected canines may show signs between 4 weeks to 6 months of age. Affected canine fall asleep faster than normal dogs and cannot stay awake for an extended period of time. In respons to emotional stimulus, affected canines may experience cataplexy: a sudden loss of muscle tone without loss of consciousness. First signs of cataplexy are buckling of both hindlimbs and drooping of the neck.
Additional information
References
Pubmed ID: 10458611
Omia ID: 703