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Gallbladder mucoceles (GBM) are buildups of thickened mucus and/or bile in the gallbladder, which can result in gallbladder rupture, infection and other complications.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Gallbladder mucoceles (GBM) are buildups of thickened mucus and/or bile in the gallbladder, which can result in gallbladder rupture, infection and other complications. It is caused by a defective ABCB4 gene found mainly in Shetland Sheepdogs.
Clinical features
Gall bladder mucocele is characterised by formation of cysts in the gall bladder. This causes hepatobiliary disease which has been recognized with increased frequency during the past several years.
Additional information
There are also studies published in which no statistically significant association could be found between the ABCB4 gen and gall bladder mucoceles.
References
Pubmed ID: 20598156
Omia ID: 1524