57,48 47,50 excl. VAT

H788

Beta Mannosidosis is a metabolic disease that causes neurological defects such as lack of coordination, seizures and deafness.

10 working days

€5,95 shipping and administration per order (incl. VAT)

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

Beta Mannosidosis is a metabolic disease that causes neurological defects such as lack of coordination, seizures and deafness. This variant of the disorder, found in the German Shepherd, is caused by a recessive mutation to the gene MANBA. The disease is severe, and affected dogs are typically euthanized on humane grounds.

Clinical features

Affected puppies start presenting at approximately 8 weeks of age with reduced growth, deafness, stiff limbs, ataxia (loss of coordination), difficulty running and navigating obstacles. The disease is painful and causes reluctance to move. Due to poor quality of life, euthanasia is typically elected for by 8 months of age.

Additional information

References

Pubmed ID: 30983534

Omia ID: 626

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

Related products