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Canine Coagulation Factor VII is an important protein involved in blood clotting in dogs.
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Specifications
Breeds | Alaskan Klee Kai, Sealyham Terrier, Welsh Springer Spaniel, Airedale Terrier, Irish Water Spaniel, American Foxhound, Beagle, Finnish Hound, German Wirehaired Pointer, Giant Schnauzer, Miniature Schnauzer, Papillon, Scottish Deerhound |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Year Published |
General information
Canine Coagulation Factor VII is an important protein involved in blood clotting in dogs. Deficiency in Factor VII causes a bleeding disorder, which can lead to dangerously uncontrolled bleeding in the case of injury or surgery. The disorder occurs in the Beagle, and is caused by a recessive mutation to the gene F7.
Clinical features
Under most circumstances, affected dogs appear healthy. However, they may bleed excessively after trauma or surgery, develop hematomas or bleeding in the body cavity, or experience persistent uterine or vaginal bleeding. Blood analysis can confirm a lack of Factor VII activity.
Additional information
References
Pubmed ID: 16961583
Omia ID: 361