Dr. van Haeringen Laboratorium B.V.

H894 Coat Colour, Oculocutaneous Albinism (OCA2)

Background

Impairment of eumelanin and phaeomelanin synthesis leads to a reduction of pigmentation in skin hair and eyes. Mutations in six different genes have been identified to cause several distinct forms of oculocutaneous albinism in humans and many animal species. Variants in the OCA gene cause oculocutaneous albinism type 2 (OCA2) in German Spitz.

Test specific information

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Age

Most coat colours and coat types are usually visible directly after birth.

Turnaround time

The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.

The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.

PLEASE NOTE
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.

Location of disease or trait

Genetic factors influencing coat colours and coat types are usually visible on the outside of an individual. Several factors may be hidden by the external variation.

Breed dependence

This DNA test is available for the following breeds: German Spitz. Additional information is available in the Frequently Asked Questions (FAQ).

Sample type

For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Swab, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.

Result

Coat colours and coat types are based on many genetic factors. For each factor, a separate test result will be returned.

Inheritance

This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).

Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.

Severity of Disease

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Code H894

Coat Colour, Oculocutaneous Albinism (OCA2)

€ 50,94 (Incl. 21% VAT)
€ 42,10 (Excl. VAT)
Quantity