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At certain DNA-tests, breeds are indicated because the mutation has been identified in these breeds. A breed can be indicated due to two main reasons. For more information see below:
• Development through scientific research:
Scientific research identifies causal mutations by linking DNA-variation to diseases and/or genetic characteristics. By comparison of the symptoms or characteristics with genetic variation in the DNA, a diagnostic test can be developed. In general, this information is published in a scientific journal. In many cases, these publications refer to limited numbers of breeds.
• Other breeds:
Mutations which have been published in a few breeds may also exist in other breeds. Often this is not published to any further extent in a scientific journal. The occurrence of such mutations in other breeds is highly possible and likely to have a comparable effect.
If a DNA test result indicates that an animal is no carrier of the mutation that causes the relevant disease, it is not a guarantee that that animal will never develop the genetic disease/characteristic in question. Specifically, mutations that cause the same symptoms could occur in other locations in the animal’s DNA.
If a DNA test result indicates that an animal is affected (or carrier), this fact is generally the basis for assuming that the animal will develop the genetic disease/characteristic.
The owner is solely responsible to determine if he/she will have an animal tested based on the above criteria.