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Dandy-Walker-like malformation (DWLM), a form of cerebellar hypoplasia, is a disorder caused by abnormal brain development, which in turn causes a lack of muscle coordination.

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Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Dandy-Walker-like malformation (DWLM), a form of cerebellar hypoplasia, is a disorder caused by abnormal brain development, which in turn causes a lack of muscle coordination. DWLM in the Eurasier is caused by a recessive mutation to the gene VLDLR

Clinical features

Affected dogs begin to present symptoms when they start to walk. These symptoms include rolling and/or leaning, hypermetric gait (overstepping while walking), tremors, loss of menace response and other difficulties with perception.

Additional information

References

Pubmed ID: 25668033

Omia ID: 1947

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3. Results

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