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K300

Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C).

10 working days

€5,95 shipping and administration per order (incl. VAT)

Only available in bundles

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C). Type A is “normal”; Types B and AB can be caused by a number of recessive mutations to the gene CMAH.

Besides being relevant for medical issues such as blood transfusion, a cat’s serotype is significant for breeding. If a kitten with Serotype A is born to a mother with Serotype B, it is at risk from the A-targeting antibodies in the mother’s milk. This causes a potentially lethal reaction known as Feline Isoerythrolysis Neonatalis (IN) or “Fading Kitten Syndrome”.

This test analyses for the rare mutation a^c, which causes blood type AB. The a^c allele is recessive to N (Type A), but dominant to b (Type B).

Clinical features

The A/B blood group system is clinically important in cats because mismatched breeding and transfusions can cause life threatening hemolytic reactions without prior sensitization. Therefore, a complete genetic characterization of all feline blood types is crucial so that genetic testing can accurately report an individual’s blood type.

Additional information

Due to the many possible mutations that can cause blood type B, it is not always possible to identify a cat's blood type through genetics alone. The serological test (K712) directly determines blood type. This test must be done with a blood sample, rather than a saliva swab.

References

Pubmed ID: 27171395

Omia ID: 119

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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